We were confident that our patient had nothing more than classic bear tracks. More specifically, such lesions are not round like most CHRPE, but more oval––almost exhibiting a football shape. 1,3 However, the shape of the CHRPE lesions seen in these patients is uniquely different than what is seen in patients with either classic CHRPE formation or bear tracks. The risk for intestinal malignancy in adults with Gardner’s syndrome is virtually 100%. Gardner’s syndrome, also known as familial colorectal polyposis, is an autosomal dominant disease that is characterized by adenomatous polyposis of the large and small intestines, hamartomas of the skeleton and various soft tissue tumefactions. The presence of multiple CHRPE lesions in both eyes should raise a concern for Gardner’s syndrome. In addition, when examined å electron microscopy, hypertrophy and hyperplasia of the RPE cells is not a significant feature in patients with bear tracks. For instance, bear tracks are more elliptical in shape than CHRPE. 2 However, there are ultrastructural differences between the two entities. In fact, it has been suggested that CHRPE and bear tracks are different expressions of the same condition. There has been some debate regarding the differences between CHRPE and bear tracks, because both presentations have a similar histopathology. The bear tracks are significantly more apparent on fundus autofluorescence, where the hyperpigmentation causes evident blockages. In our patient, they were predominantly located in the nasal retina, inferiorly in the right eye and superiorly in the left. They are often grouped in one sector of the fundus. For that reason, these lesions have been referred to as “bear tracks.”īear tracks are congenital anomalies that are characterized by small, sharply circumscribed, variably sized, pigment spots. In fact, if you use a little imagination, you almost get the impression that the pigmented lesions look like the paw prints of an animal that has been walking around the retina. ![]() One particularly interesting CHRPE variation presents as clusters or groups of lesions, as seen in our patient. Fundus autofluorescence reveals the presence of multiple pigmented lesions (O.D. However, there are variations in how CHRPE may present.ģ, 4. 1,2 Its color can vary from dark brown or black to gray, and lacunae can be present within the lesion.ĬHRPE are benign lesions that are usually discovered as an incidental finding during a routine eye exam. A typical CHRPE is a solitary, round, flat, well demarcated, hyperpigmented lesion that is present at birth. The multiple lesions seen in both eyes represent a form of CHRPE. What is the significance of these lesions? Note the peculiar lesions scattered throughout the retinae.Ģ. Congenital hypertrophy of the retinal pigment epithelium (CHRPE).ġ, 2. What are the peculiar fundus lesions seen in both eyes?ī. Additionally, we performed fundus autofluorescence ( figures 3 and 4).ġ. We noted multiple, peculiar lesions in each eye ( figures 1 and 2). The vessels were of normal caliber and the maculae appeared normal. His intraocular pressure measured 13mm Hg O.U.ĭilated fundus exam showed clear vitreous without cells, as well as moderate-sized cups with good rim coloration and perfusion O.U. The anterior segment examination was unremarkable. His pupils were equally round and reactive to light, with no afferent defect. Confrontation visual fields were full to careful finger counting O.U. With hyperopic correction, he was able to see 20/20 O.U. On examination, his uncorrected visual acuity measured 20/200 O.D. ![]() He took several medications, including Isentres (raltegravir, Merck), Prezista (darunavir, Janssen Therapeutics), Norvir (ritonavir, Abbott), PhenaTrim (weight loss supplement), acyclovir and lisinopril. He did not know his CD4 number or his viral load, but indicated that he saw his doctor every three months. Additionally, he reported hypertension and borderline high cholesterol. His medical history was significant for HIV, which was diagnosed in 1992. The patient said that the glasses helped, but he still struggled to see. He reported that he only wore +2.00D over-the-counter reading glasses. A 55-year-old black male presented with complaints of blurred vision at both distance and near.
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Restoration wont be much of a help with so much regen going on. Most classes have regen skills strong enough to keep them above healthgate plus your Elated skill adds to thier regen keeping them alive. So for mobbing you can remove all your points from Quicken and add it to Res and Scorn So you dont loose much DPS in combat. So dont spam Phaselock for slag, you have enough slag to keep the raid boss slagged and if you're going co op you'll need your phaselock to keep your buddies up. The Grog will allow for easy healthgating when your in trouble. A lot of the kill skills will go to waste so if you wan you can add them to Quicken, Fleet, Accelerate or anywhere you see fit. To kil a raid boss I did add elemental Bee shields to provide added defense from Pete, DRagon, Vorac and other bosses, not just raids, if you wanna farm for things and killing things faster. For added healthgating a Transfusion will bring health trails your way. Once you get a kll, all your DoTs, plus damage stack up to almost instatly bring you to full healths while your shields recharge and soak up the rest of the DoTs on you. The regen you get you get with Elated will help you keep up with a DoT while you apply your wn DoTs with the help of Ruin and Chain Reaction. Healthgating with Maya will not be a problem whatsoever. Then you focus on your phaselocked enemy for your sweet release. What you want to do is phaselock the most dangerous enemies and kill at least one of the enemies that get pulled in with Converge to active Life Tap and your other pretty skills. With this build you can but you sould still be careful, the gear will keep you alive so long as you kill things. So running in guns blazing at OP 8 will never go well, unless your Sal and even he can have trouble. Plus with the bone and Binder COM you already have good cooldown. The small cooldown rate is nice but even at 5/5 the skill will take some time. Here is where the optional skill points go. The damage done by a reflected bullet adds up to health with Life Tap. ![]() Having the damage reduction is nice but really what you want is chance to reflect. It's about hitting hard and taking hits.Īnother skill that works well with Life Tap. Your main weapon, Sandhawk, wont suffer at all with the little less damage. This will help you get Life Tap and all your other sweet kill skills for even more damage and survival.Ī little boost to your overall damage. ![]() Some people dont like this skill but I enjoy the added recharge delay this skill, plus Inertia will help keep your sheilds up.Įxactly as the previous skill says, recharges 3.2% of your shield capacity per second helping you keep your sheilds up.Ī very useful skill when grouping enemies. After a recent patch, I think recent, Maya got a huge buff to her skills, Cloud Kill will kill slagged flesh targets at OP 8 and keep you alive with Life Tap.Ĩ0% gun damage on enemeis over 50% health. "this skill suuuucks it does no damage and other words!" Shuddup. This, plus Converge and Wreck, will allow you to damage, possibly kill, anyone near the bubble. This skill will add fire damage to your gun when you are in FFYL (Fight For Your Life) Why this skill you may ask if its a sure fire way to survive? There wot be a day in Pandor where you wont go down! Equip a slag weapon, something with a high fire rate, and viola, your back up!Īha! Here's a skill that allows you to wreck things with Wreck! While you have someone in your Phaselock, any bullet, this sadly doesnt work for E-tech SMGs, has a 40%, almost 50, chance to bounce off an enemy and hit another. The reasoon for this skill is it adds a reliable damage source that will keep you alive with Life Tap. reload speed lets you get those full clips in to keep spamming your bullets plus you get more bullets in your mag. This will make your Sandhawk another Grog Nozzle so long as you keep killing scrubs lol.ĥ/5 in this skill for the DPS. This includes gun, grenades, melee, jumping on enemies and other forms of damage. Which means you ill get 4.8% of your health back based on all the damage you do. This skill give you a 4.8% of life steal. Kinda useless for raid bosses, unless its Terra or a few others. Now for the first kill skill in the build! ne that will make you almost invincible against bandits and bosses. Don,t know what healthgate is? My previous guide explains it. this will help you stay above healthgate. This skill is another one of your health skills. The fun part is getting the enemies grouped up and destroying everything! A skill that activates when you have an enemy in your phaselock. ![]() The melee damage is neglegable.Ī very sweet skill indeed, if your health is below half, one kill will keep you alive for longer. This is especially useful when you come across an Ironclad or Burning Psycho. ![]() More recently Thiel has drawn criticism for his political lobbying, which included a high-profile endorsement of Donald Trump. Elon Musk denies report that hes been staying in a 12 million lavish waterfront Austin. Musk, the company’s largest shareholder, owned 11. Portnoy later joined Thiel at his hedge fund, Clarium Capital, and the big-data firm Palantir, founded after PayPal was acquired in 2002. Elon Musk Denies Living in PayPal Mafia Members Austin Mansion. PayPal was a huge enabler for eBay, and in October 2002, the company decided to make PayPal its own, and acquired it for 1.5 billion in stock. So the thing about Elon Musk is that he’s cliqued up specifically with the so-called PayPal Mafia. Here's where the original members have ended up. Musk has had issues with the account for a long time, and offered Jack Sweeney 5,000 to delete the account in 2021. The 'PayPal Mafia' formed in the early 2000s, and includes everyone from Elon Musk to the Yelp founders. The account tracked the private jet of Musk with publicly known data. He said he was hired in 1999 by Thiel, then the CEO of the startup Confinity, because they'd bonded over a list of books he'd read while traveling around Europe. The ElonJet Twitter account was started in June 2020 by Florida student Jack Sweeney, a fan of Musk. Elon Musk (Tesla, Space X, Solar City), Peter Thiel (Palantir, Founders Fund, author of Zero to One, you can read Blake Masters actual course. He was a vice president of finance at PayPal for three years. Portnoy appeared on the podcast to discuss his memoir, "Silicon Valley Porn Star," which details his early career in Silicon Valley as well as his descent into and recovery from a porn addiction. And over time, gradually, the executives from the PayPal team who had no prior experience in the financial-services industry wound up ascending in the corporate culture and hierarchy, and I think possibly because they weren't weighed down by legacy ideas of how things should be done," he said. "PayPal merged with X.com, and X.com had a lot of former financial-industry people. After selling PayPal, Elon Musk bought a McLaren F1 so that he could race. Account icon An icon in the shape of a person's head and shoulders. ![]() I was told it was because Netflix used flash in its log-in screen. In the past Roboform would, unbelievably, not fill out the login for Netflix. It doesn't happen often but when it does it is kind of infuriating. One, is that it actually balks at filling out some forms and passwords. There are a few real issues with the program, for me at least. I believe other password managers are available for free, but Roboform is a subscription service which I've used for many years, regularly renewing my subscription, partly out of inertia and not wanting to learn another manager. It is a fairly complex program with many features, that takes some getting used to. It does a fairly good job of filling out forms and passwords. Roboform is insulting its user base and should change that policy immediately. This might be a money grab or power grab, but Roboform should not insult paying customers by disabling a free service in favour of a paying service. That's true, but I'm intelligent enough to decide that for myself, especially when Chrome fills in forms that Roboform mysteriously will not. When I complained to Roboform support one thing I was told was that browser managers and not as secure as form fillers like Roboform. I find that infuriating, as Roboform will not fill in some forms that Chrome always will. Most recently Roboform stopped integrating with Chrome form filler and actually disabled it. The longer the list, the harder to spot what one is looking for. So one ends up with a long list of entries to sort through. I've been using that function a lot, but one of the problems is I see no way to create separate folders for information. Roboform also has a function called Safenotes, which I like, where one can save encrypted personal information, such as bank account numbers, social security numbers, etc. I continue to use Robofom, as stated, partly out of inertia. My recommendation to the Roboform technical team is that they incorporate more security in the use of their software, of rest I think it is an excellent software that is very easy to use and free. Currently my Roboform session is protected because I have other two-step authentication software that keeps my account completely secure. Roboform should incorporate higher levels of security so that passwords can be used. Without a doubt Roboform is one of the most complete software I have used for these purposes and I would not change it for anything. ![]() Another great benefit that Roboform gives me is that I can customize my login, always remembering which passwords I have stored in the central panel and for which software and web pages I should use them. Roboform not only saves my passwords, but it is also quite intuitive and when I enter the pages or software that require a password, Roboform adds the self-filling of the information, making it much easier for me to use the software and web pages. For example, I could mention that Roboform works for me as a password pointer, since I manage several software and online accounts which I depend on to meet my work goals. Roboform has certain benefits that complement my work routine. Taking this aspect into consideration I have a software suite that I use to maintain the security of the legal documents I produce, and among those is Roboform, a very complete software that allows me to manage my passwords from the comfort of a central panel that manages them, in short, Roboform is the best password manager I have ever used. In my current job it is always very important to maintain high levels of security and the utmost confidentiality when preparing legal documents for the company. ![]() ![]() With VLC MOD APK, the entertainment never stops. It’s an intuitive way to interact with your media player. Swipe, tap, and pinch to zoom effortlessly, as if your device understands your every move. Navigating through your media library becomes a breeze with gesture controls in VLC MOD APK. From customizable equalizers to various sound presets, tweak the settings to suit your preferences and indulge in exceptional audio quality. Not only does VLC MOD APK excel in video playback, but it also offers advanced audio features that enrich your listening experience. Whether it’s a movie, TV show, or a homemade video, VLC MOD APK ensures every moment is a visual treat. Enjoy high-definition videos with smooth playback and superior image quality. VLC MOD APK takes video playback to another dimension with its enhanced capabilities. Now, immerse yourself in the content you love, undisturbed. VLC MOD APK offers an ad-free experience, allowing you to watch your favorite videos or listen to music without any interruptions. Say goodbye to those annoying ads that disrupt your media enjoyment. It’s like VLC on steroids, giving you unparalleled control over your media content. This MOD APK takes the exceptional capabilities of VLC and elevates them to a whole new level, providing users with additional features and functionalities that are not available in the standard version. VLC MOD APK is a modified version of the renowned VLC Media Player, which is popular for its versatility and ability to play almost any media format flawlessly. In this article, we delve into the world of VLC MOD APK, its remarkable features, and how it elevates your media consumption to an entirely new level. If you are seeking an unparalleled media player with enhanced features and limitless possibilities, look no further than VLC MOD APK. How frequently are the MOD features updated?.Does VLC MOD APK support all media formats?.Can I use VLC MOD APK on multiple devices?. ![]() ![]() ![]() It’s not the easiest song on the list, but it should give you a good challenge. This version is designed to be fingerpicked. I bring you first the wonderful children’s classic “Away in a Manger.” This beloved Christmas song is attributed to Martin Luther, and ranked as the second most popular Christmas carol of all time according to a 1996 Gallup poll. So, the first three tabs are in standard ukulele tuning of G C E A. I’ve included links with each song which allow you to download and print the ukulele tabs. The other six songs are in ADAD or DDAD tuning, and should give you endless joy! And when you’re sitting by your tree, sipping on your eggnog, and lightly picking out these fun holiday classics on your brand new ukulele, think of me, and raise a glass of nog in honor of your favorite ukulele writer this year! These tabs are great for the ukulele, and some of the other four-stringed instruments can be tuned to this tuning as well, so Santa Willy has given you plenty to mull over this holiday season. I have also included three popular ukulele Christmas songs in standard tuning G C E A. So if you’re a teacher who teaches multiple instruments, or a student with other friends who play, then the ADAD and DDAD tabs are perfect for you. The nice thing about Dead Man’s Tuning (an old time fiddle tuning), is that it works for mandolin, ukulele, banjo and violin, so you can use these tabs to play Christmas tunes with any of these instruments. The tabs for these holiday classics originally came from my book “ Mandolin Dead Man’s Tuning: Christmas Edition.” If you’re interested, with the book, you can learn more of these fun songs (over 30 are included in the book). Most of these tunes are simple to play, and I have included the chords, the tabs, and the tunings that you need to start playing these Christmas ukulele songs. Ho! Ho! Ho! While, I don’t look a lot like Santa Claus (well, apart from the beard and pudgy belly), I’m bringing you a sack full of holiday cheer this month with Christmas ukulele songs! That’s right, I’m going to give you fun holiday songs that you can play on your ukulele. From “Jingle Bells” to “Mele Kalikimaka,” learn these Christmas ukulele tabs with Winston, NC teacher Willy M… The holidays are right around the corner get in the spirit with these classic Christmas ukulele songs. ![]() This will allow you to install other upgrades that require more weight if you’re using lightweight engines or toughen up your engines to take more damage if they are armored. Armored engines help you soak up more damage, while lightweight engines help you save weight so you can upgrade more demanding systems. Upgrading your engines is very important. You must send someone out to extinguish engine fires or risk losing the entire engine if you do not install this. This will allow you to put out more engine fires per flight without sending someone onto the wing to put it out. Regardless of how good you are or how armored you may be, you will encounter engine fires, and these need to be put out quickly to make them run smoothly again. Heavier electric systems will make you unable to install other upgrades around the bomber.Įngine fire extinguishers really come into their own when in combat. Your engineer will spend more time fixing things when they could do other things around the bomber. Your electrics onboard will run much better, with less time spent fixing it when it breaks. Electrical systems also allow your radio operator to call for backup during intense combat, so make sure it works efficiently. Your electrical system is very important to the crew, allowing your radar to function properly and identify enemy aircraft in your area. To help you get there quicker, here are the upgrades you should earn first to help make your missions run smoother and sustain fewer casualties in your missions. Constantly managing your weight and upgrades can be challenging, but you’ll soon find a play style that you can use to your advantage. ![]() Getting started on Bomber Crew can initially be a little daunting due to the complex upgrading system. I am the ceo, and I’m really excited about it.” “I’ve always been orchestrated or directed to be what the program, commercial or brand wanted, and I’ve never done anything for myself, so this was a big departure. She loved the idea of being the boss of her own company. She told WWD the idea came to her after she grew tired of cutting up her father’s tailored shirts and taping the collar and French cuffs to her neck and wrists. She said she could not believe there was not a similar product on the market: “The closest you could get to it is actually a Playboy outfit, or something for a male ice skater,” she said in March during an interview. Her aim was to fuse the comfort of a bodysuit with the sophistication of a formal men’s shirt. “It’s all brilliantly made, so if you’re going to do a cartwheel, you don’t have to straighten yourself out afterwards. The slimming bodysuit created by Tara Palmer-Tomkinson. She designed and manufactured a range of luxury onesies, which she called “kubbies.” ![]() Last year, she realized a long-held dream, financing and running her own business, Desiderata London. One of her few public appearances was at the wedding of the Duke and Duchess of Cambridge in 2011, where she wore a draped cobalt blue dress that she designed herself, teaming it with a hat in the same hue. In the last decade, Palmer-Tomkinson retreated from the limelight and focused on treating her drug problems. She also took her vibrant personality to the small screen, starring in the British reality series “I’m a Celebrity, Get Me Out of Here.” Over the years, she also appeared in TV ads, wrote a few novels, and even recorded an album called “Flawed.” She was also a regular on the slopes of Klosters, Switzerland, where she had a home, and would sometimes ski with the royal family. In 2007, Palmer-Tomkinson released a book called “The Naughty Girl’s Guide to Life,” her personal version of a self-help book, with advice on topics such as how to talk your way into getting Chanel freebies how to hitch a free ride on a private jet, and what to do if you wake up in bed with your boss. Palmer-Tomkinson was happy to share the scandalous behind-the-scenes goings-on in London’s party scene, documenting her exploits in a weekly, ghost-written column for the Sunday Times during the Nineties. Like so many she battled the demons of addiction, she will be missed,” said Mellon, upon hearing of her friend’s passing. I have vivid memories of Tara always adding life and fun to any dinner or party in London. “I’m so saddened to hear the news of Tara passing. Palmer-Tomkinson was a fixture of the party circuit - and the gossip columns of the British tabloids - throughout the Nineties, a member of a group of young, wealthy, upper-crust women who also included the-then Tamara Yeardye (later Mellon) and Tamara Beckwith. Palmer-Tomkinson’s elder sister Santa Montefiore is the best-selling author of romantic novels such as “The Girl Inside the Castle” and “Daughters of Castle Deverill,” and her brother-in-law is Simon Sebag Montefiore, an historian and writer of and fiction and nonfiction. Van Cleef & Arpels to Preserve Rose Garden at Dumfries House, Scotland ![]() ![]() An illustration of seven pumpkins placed on top of the hay with autumn leaves falling in the. Every Pumpkin coloring page is a printable PDF and/or can be downloaded. Click the Pumpkin pictures or illustrations you like and you’ll be taken to the PDF download and/or print page. ![]() These printables are for personal, non-commercial use only. Welcome to our collection of free PUMPKIN coloring pages. Puzzle games: Click the Scared Pumpkin coloring pages to view printable version or color it online (compatible with iPad and Android tablets). To download, simply click on the image or text-link underneath the image. Our coloring sheets are high-resolution letter-sized printable PDFs. From simple pumpkin outlines for preschool kids to color in, to more detailed designs for big kids, we hope you find a picture that you like! Pictures, Pumpkin Coloring Sheet, Adult Coloring Pages. Scroll down the page to see all of our pumpkin pictures. Scary Pumpkin Face Super Coloring Scary Coloring Pages, Halloween Pumpkin Coloring Pages, Halloween. You can print or download them to color and offer them to your family and friends. A warm blanket, a good movie, and some coloring can make any chilly day better!Īnd I can't think of a better way to get ready for Halloween and Thanksgiving than coloring some pumpkins! Our pages include carved pumpkins and Jack O'lanterns, trick-or-treat-themed pictures, pumpkin activity sheets, and more! It's a simple and enjoyable way to get into the spirit of the season and sure to keep the little ones busy before they head out trick or treating! Free printable Happy Halloween Pumpkin coloring pages for kids of all ages. They're a fun free activity, and there's something for everyone, from kids to adults. If you're looking for a relaxed way to spend those cold fall days, our pumpkin coloring pages are perfect. |
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